A formula from the beginning of the 20th century. The author added Job's tears to the original Er Miao San (Two-Marvel Powder) by the famous Zhu Dan-Xi from the 15th century, which had been expanded into San Miao San (Three-Marvel Powder) in the 16th century, thus increasing the formula's ability to drain dampness. Its use is broad: various manifestations of damp-heat, primarily in the lower part of the body.
Perhaps the most well-known and famous use of Si Miao Wan is in the treatment of painful joint conditions, so-called Bi-syndromes, which in this case are attacked by damp-heat. The joints (especially the knees and ankles) are swollen, red, hot, and have limited mobility. In addition to Bi-syndromes, which are characterised by "excess", the formula is also used for so-called Wei-syndromes, which are also caused by damp-heat but manifest more with signs of deficiency, such as weakness or atrophy of the lower limbs, severe tingling to numbness in their peripheral area, a feeling of heaviness and mild swelling, and flaccidity. It is therefore used in the treatment of rheumatoid arthritis, joint involvement in rheumatic fever, gout, or psoriasis, where the arthritis has a "hot" character. Another common use is the treatment of manifestations of damp-heat in the lower burner, primarily in the form of gynaecological inflammation with yellow, foul-smelling discharge, and in men for prostatitis (inflammation of the prostate). Damp-heat in the lower part of the body can also manifest in the form of weeping, red skin conditions, often as eczema, or as red, hot swelling of the lower limbs. Here too, Si Miao San will be an essential part of herbal treatment.
Without modification, contraindicated in cases of liver and kidney yin deficiency, as further injury to yin is possible.
Caution when administering during pregnancy – only under the supervision of an experienced TCM practitioner!
During treatment, it is necessary to avoid sweet, greasy, and fatty foods in the diet.
| Preparation | Chinese | Czech | Latin |
| Sheng | Huang Bai | Amur cork tree, bark | Cort. phellodendri |
| Chao | Cang Zhu | Atractylodes, rhizome | Rhiz. atractilodis |
| Sheng | Chuan Niu Xi | Achyranthes, root | Rad. achyranthis |
| Sheng | Yi Yi Ren | Job's tears, seed | Sem. coicis |

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